ICG-17 Programme
7 - 9 SEPTEMBER 2022
Riga, Latvia

Keynote Speech: Scalable single-cell transcriptomics with full-length coverage
Prof. Rickard Sandberg, Karolinska Institute, Sweden

A multi omics approach to study the molecular and cellular organization of the brain (in health and disease)
Prof. Jan Mulder, Karolinska Institute, Sweden

Harmonized single-cell landscape, intercellular crosstalk and tumor architecture of glioblastoma
Prof. Henk Stunnenberg, Prinses Máxima Centrum, Netherlands

Improvements in RNA-seq in Bulk & Single Cells at MGI Joint Lab at Imperial College London
Nik Matthews, Imperial College London, United Kingdom

Stereo-seq introduction and Grant
Dr. Jia Hui Khoo, BGI Research Europe, Dr. Nicole Neubauer, MGI, Germany
Global success stories & major projects - How can research add value to the community
Panelist Discussion:
Prof. Janis Klovins, Latvian Biomedical Research and Study Centre, Latvia,
Dr. Maike Seifert, Karolinska Institutet, Sweden,
Filips Oleskovs, MGI, Latvia,
Dr. Mathieu Almeida, INRAE MetaGenoPolis, France

Introducing HotMPS; Bringing the Power of choice to sequencing
Dr. Weilin Liu, MGI, Netherlands

Runx3- and Zbtb46-dependent gene expression profiling with DNBSEQ G400
Dr. István Szatmári, University of Debrecen, Hungary

Deep exploration of the human intestinal microbiota in association with health in the era of Big Data
Dr. Mathieu Almeida, INRAE MetaGenoPolis, France
ICG-17 sponsored MGI Latvian Facility Tour

Keynote Speech: From genomic research to precision medicine in complex diseases
Dr. Triin Laisk, University of Tartu, Estonia

A roadmap to achieve pharmacological precision medicine in diabetes
Prof. Ewan Pearson, University of Dundee, United Kingdom (online)

The Human Protein Atlas and Precision Medicine
Prof. Mathias Uhlén, KTH Royal Institute of Technology, Sweden


Personalised genomics in exercise and sports medicine: The future is now
Prof. Yannis Pitsiladis, University of Brighton, United Kingdom

Extracellular vesicles – carriers of cancer-derived biomarkers in liquid biopsies for the detection and monitoring of cancer and prediction of response to therapy
Prof. Aija Line, Latvian Biomedical Research and Study Centre, Latvia

Personalized medicine landscape in Africa
Rizwana Mia, South African Medical Research Council, South Africa

The implementation of complex genetics in health care settings: translatable use of research data and the importance of Million Genomes Initiative.
Prof. Andre Uitterlinden, Erasmus Medical Centre, Erasmus University Rotterdam, Netherlands

Epigenetics of type 2 diabetes mellitus and weight change — a tool for precision medicine? Nature Reviews Endocrinology
Prof. Charlotte Ling, Lund University, Sweden (online)

Comprehensive molecular Tumor Analysis (CMTA) integrating WGS/WES & RNAseq to guide clinical decision-making in oncology
Dr. Marie-Laure Yaspo, Alacris Theranostics GmbH, Germany

Gut metagenome associations with extensive digital health data in a volunteer-based Estonian microbiome cohort
Dr. Elin Org, University of Tartu, Estonia

Diagnosing Rare Diseases: Beyond the exome.
Prof. Olaf Riess, University of Tuebingen, Germany

Applying multi-omics approach to understand the pathophysiology and treatment efficacy of type 2 diabetes.
Prof. Janis Klovins, Latvian Biomedical Research and Study Centre, Latvia

The gut microbiota and mental disease
Prof. Karsten Kristiansen, University of Copenhagen, Denmark

Preterm labor
Prof. Mark Johnson, Imperial College London, United Kingdom

Announcement about INTEGROMED project and invitation to join consortium
Prof. Janis Klovins, Latvian Biomedical Research and Study Centre, Latvia

Keynote Speech: Genome level resolution metagenomics - from viruses to eukaryotes
Dr. Rob Finn, The European Bioinformatics Institute (EMBL-EBI), United Kingdom

Circulating microbiome in patients with portal hypertension
Dr. Jurgita Skiecevičienė, Lithuanian University of Health Sciences, Lithuania

RNA sequencing identifies signatures in maternal blood that predict imminent preterm birth
Dr. Stephen Lye, Lunenfeld-Tanenbaum Research Institute Mount Sinai Hospital, Canada

Non-invasive Prenatal Testing - Hungarian Experience
Anna Kekesi, Istenhegyi GeneDiagnostic Center, Hungary


Keynote speech: Advancement of biobanks for next generation scientific needs and discoveries
Dr. Vita Rovīte, Latvian Biomedical Research and Study Centre, Latvia

Biobanks - platforms for clinical trials that develop precision medicine
Prof. Colin Palmer, University of Dundee, United Kingdom

Genomic based Electronic Health Records
Prof. Hananiel Prakasya Wijaya, Granostic Diagnostic Lab, Indonesia

Biobanking and Innovation
Prof. Akin Emmanuel Abayomi, Lagos State Ministry of Health, Nigeria (online)




Harnessing large biobanks from diverse populations for precision medicine
Prof. Zhengming Chen, University of Oxford, United Kingdom

From the physical to the digital spheres: biobanking perspectives on standards, guidelines and ethics
Dr. Zisis Kozlakidis. IARC/WHO, United Kingdom (online)

Lessons learned in publishing health data, and aligning this with the UNESCO Open Science Recommendations
Dr. Scott Edmunds, GigaScience Press, Hong Kong


Keynote Speech: A Decade of Women in Science: Gains and Losses
Dr. Laurie Goodman, GigaScience Press, United States of America

Clinical application of viral sequencing: from sequencer to bedside
Dr. Teresa Cutino-Moguel, Barts Health, United Kingdom

The implementation of high-throughput sequencing - Serbian experience
Dr. Ivana Morić, University of Belgrade, Serbia

Molecular Diagnostics for Shrimp Farmers: Learning from Covid-19
Dr. Sidrotun Naim, IPMI International Business School, Indonesia (online)
Keynote Speech: Improved SARS-CoV-2 sequencing surveillance allows the identification of new variants and signatures in infected patients
Prof. Davide Cacchiarelli, Telethon Institute of Genetics and Medicine, Italy

Tracking Sars-CoV-2 variants of concern in Wastewater: A South African Perspective
Prof. Craig Kinnear, South African Medical Research Counci, South Africa (online)

Tackling Long COVID with global Host Genetics Initiative collaboration
Dr. Vilma Lammi, FIMM Technology Centre, Finland

Multiomics approach in the identification of molecular footprints of SARS-CoV-2 infection
Laura Ansone, University of Latvia, Latvia

Detection of Sars-CoV-2 RNA in wastewater: Importance of viral lineage and population size assessment
Dr. Davids Fridmanis, Latvian Biomedical Research and Study Centre, Latvia



Registration
Registration
Registration
Break
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11:40 - 13:25
14:25-17:50
09:00 – 11:10
18:35
14:20 –18:35
09:00 – 13:20
15:30-18:30
12:00-14:05
09:30 – 11:35
09:00 – 09:30
17:00 – 17:25
16:35– 17:00
15:45– 16:10
15:20– 15:45
14:55– 15:20
14:25– 14:55
13:00– 13:25
12:35– 13:00
12:10– 12:35
11:40– 12:10
10:45 – 11:10
10:20 – 10:45
09:55 – 10:20
09:30 – 09:55
09:00 – 09:30
17:45 – 18:10
17:20 – 17:45
16:55 – 17:20
16:30 – 16:55
15:40 – 16:05
15:15 – 15:40
14:45 – 15:15
14:20 – 14:45
12:30 – 12:55
12:05 – 12:30
11:40 – 12:05
11:15 – 11:40
10:20 – 10:45
09:55 – 10:20
09:30 – 09:55
09:05 – 09:30
09:00 – 09:05
13:40 – 14:05
12:50 – 13:15
12:25 – 12:50
12:00 – 12:25
11:10 – 11:35
10:45 – 11:10
10:20 – 10:45
09:30 – 10:20
Workshop Agenda Day 3: Hosted by BMC



Workshop Agenda Day 2: Hosted by BGI Group



Workshop Agenda Day 1: Hosted by BGI Group
Friday 9 September 2022
Thursday 8 September 2022
Wednesday 7 September 2022
13:15 – 13:40
Dr. Zhouchun Shang, MGI, BGI Research, China
Prof. Fred Dubee, BGI, Canada
Prof. Janis Klovins, Latvian Biomedical Research and Study Centre, Latvia
12:55 – 13:20
18:10 – 18:35
Session Chair: Dr. Zhouchun Shang, MGI, BGI Research, China
Spatially resolved gene expression profiling with single-cell resolution
Session Chair & Panel Lead: Dr. Riddhi Patel, MGI, Germany
ICG-17: OMICS for all
Session Chair: Prof. Janis Klovins, Latvian Biomedical Research and Study Centre, Latvia
Leveraging multi-omics approaches and the promise of microbiome

Session chair: Prof. Valdis Pirags, Pauls Stradiņš Clinical University Hospital, University of Latvia, Latvia
Precision medicine, the future of healthcare
Break
17:25 – 17:50
18:00
Welcome and Opening of ICG-17, Riga

With the development and evolution in NGS studies for all the different omics fields, like genomics, metagenomics, transcriptomics and others, it is being recognized that understanding of mutually influencing processes might be possible with the integrated multi-omics approach. In this session we may discuss the novel metagenome associative research, multiomics insights into biological events, the need for a multi-ecosystem approach to microbiome studies, links between different omics areas and the mechanisms of action for different diseases.

Precision / Genomic medicine has helped to guide healthcare providers to diagnose rare genetic disorders, to monitor the threat of drug resistance, provide genetic contributions to a patient's health and susceptibility or resilience to disease, or their response to therapeutic interventions. As a result genome sequencing and research into the genomic changes associated with certain disease, including defining cancer types and subtypes for example, has shown a role to play in the future of healthcare and medicine by providing patients with a more precise diagnosis, and therefore a more personalized treatment strategy. In this session we may discuss personalized medicine developments, the international consortium for personalized medicine and project that aims to identify areas of mutual interest for the collaboration in health and PM research, the importance of genomics in oncology and others.

Closing of day
Session Chair: Dr. Davids Fridmanis, Latvian Biomedical Research and Study Centre, Latvia
Multidisciplinary view on COVID-19 Research

Globally multidisciplinary consortiums have been working proactively with local governments and leaders in the research community to mobilize a coordinated response to the global emergency caused by novel coronavirus COVID-19. Genomics in particular has allowed researchers to identify new variants, provide an understanding on how the virus spreads, unravel how the immune system responds, understanding of why some people appear minimally affected while others are severely impacted, and which pharmaceutical strategies might optimally help reduce the spread and alleviate symptoms for example. This has caused a global emergence in genomics approach to disease outbreaks and understanding of disease progression, including long COVID. In the session we may discuss the importance of the global emergence of genomics to fight outbreaks, discussing the real-time assessment of community transmission, focus on understanding long covid from scientific sessions and Covid-19 host genetic initiatives.

Session Chair: Dr. Vita Rovīte, Latvian Biomedical Research and Study Centre, Latvia
Woman in science

Session of women scientists brings together top women scientists in the field of life science and big data research, covering a wide range of fields of life science, including evolution, omics, cancer, complex diseases, reproductive health, technology development and bioinformatics.

Session Chair: Cynthia Potter, MGI, Wales
Role of biobanks and health data in personalized medicine development

Biobanks provide an indispensable infrastructure for modern research with systematic collections of human biological materials, associated clinical and lifestyle data, and an accumulation of vast amounts of research findings, including participants’ genomic data. From a research perspective the interest in biobanking continues to intensify however many profound legal and ethical challenges remain unresolved. In this session we may discuss the role of biobanks and health data management in personalized medicine development through data safe havens, firsthand response from large Biobanks, and overall ethics surrounding science.

Understanding the complexity of genes functions requires spatially resolved gene expression profiling with single-cell resolution. Single-cell and Stereomics are new eras for genome research, that represent a major advance toward the systematic understanding of tissue complexity. In this session, we will discuss with leading scientists the advantages of stereomics and single-cell research and talk about their results and progress in single-cell analysis and stereomics. The agenda will include items about single-cell full-length RNA research using Oxford Nanopore devises and C4, Smart-seq automation and others.

Closing of Event
Dr. Zhouchun Shang, MGI,BGI Research, China
Prof. Janis Klovins, Latvian Biomedical Research
and Study Centre, Latvia

ABOUT ICG-17, Riga

Over the last 17 years, the International Conference on Genomics (ICG) has been the meeting point for leaders in the emerging field of Genomics to meet and share their experience, knowledge, insights, and questions, to advance understanding and craft collaborations. An integral component of the International Conference on Genomics, ICG-17, Riga will bring together in Riga Latvia, high level scientists, practitioners and institutional executives from Europe and Africa and an international team of expert speakers under the theme OMICS FOR ALL to explore the leading edge in scientific areas. ICG-17, Riga will be a European branch event alongside the Annual International Conference of Genomics hosted in China, which will take place in the same week. In addition participants will be given an information rich tour of the new MGI facilities in Riga and the opportunity to meet the leaders of BGI/MGI Europe and Africa. The event will be both onsite and streamed for remote viewing.

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